PAX8 and ovarian carcinoma: Our results clearly highlight the effect of PAX8 loss on the migratory properties of the cells demonstrated by the significant reduction in the cell migrated area of PAX8-silenced cells with respect to control cells both in Primary hFTSEC and all epithelial ovarian cancer cells that were analyzed (SKOV3, KURAMOCHI, OVSAHO and PEA1) (Fig. 1a).