Therefore, we employed extended comparison methods (Supplementary Table 5) to assess presence versus absence and there was emergence of weak intensity of epithelial nuclear RUNX3 in dysplastic BO, compared with normal mucosa (p = 0.013), non-dysplastic BO (p = 0.001) and oesophageal adenocarcinoma (p = 0.002). Here, RUNX3 is linked to bronchiolitis obliterans syndrome.