Compared to FASN-overexpressing cells, knockdown of FABP5 in FASN-overexpressing cells (FASN/shFABP5) significantly reduced luciferase signal in the primary tumor, whole mouse, and femurs in vivo (Fig. 6C), confirming that FABP5 knockdown suppresses the ability of FASN to promote metastasis. The gene discussed is FASN; the disease is neoplasm.