Hippocampal neurons treated with SCH showed upregulation of energy-efficient metabolic enzymes including cytochrome b-c1 complex subunit 1(also known as Cytb-c1 or Uqcrfs1) and succinyl-CoA:3-ketoacid CoA transferase 1, mitochondrial precursor (Oxct1). The gene discussed is UQCRFS1; the disease is spindle cell hemangioma.