As we expected, bone marrow transferred from Cav-2 KO mice significantly suppressed LLC growth in WT mice and the replacement of WT bone marrow on Cav-2 KO mice induced LLC growth, suggesting that Cav-2 deficiency and Cav-2 expression in bone marrow-derived cell types is important for suppressing and promoting tumor growth, respectively. Here, CAV2 is linked to neoplasm.