The average tumor mass was approximately 1.78 ± 0.52 g and 0.56 ± 0.20 g for WT mice without bone marrow transfer and for WT mice with Cav-2 KO bone marrow transfer, respectively (Fig. 5E), resulting in significant (p < 0.05) and nearly 3-fold reduction in tumor mass by Cav-2 KO bone marrow transfer (Fig. 5E). This evidence concerns the gene CAV2 and neoplasm.