CAV2 and neoplasm: However, due to the increased total TAM infiltration (CD11b+F4/80+ cell), when the percentage of M1-like TAM and M2-like TAM is expressed relative to total cells in tumor (calculated by percentage of M1 or M2-like TAM multiplied by percentage of CD11b+F4/80+ cells), there is a nearly 3-fold increase in the percentage of M1-like TAMs and an over 2-fold increase of M2-like TAMs in LLC tumors from Cav-2 KO mice compared to WT mice (Fig. 4C, left and central panels).