To provide a more direct evidence for the ability of Cav-2 KO bone marrow-derived hematopoietic cells to suppress tumor growth in WT mice and for involvement of M1-polarized TAMs, in addition to described previously bone marrow transfer, we performed experiments involving s.c. co-injections of Cav-2 KO vs. WT bone marrow with LLC cells into WT mice as described in Methods. Here, CAV2 is linked to neoplasm.