NDRG1 and neoplasm: Similar to HCT116 cells, when NDRG1 was silenced in SW1116 cells, the tumor weight and volume dramatically increased compared to the relative control group (1292 ± 110.6 vs. 329.4 ± 72.72 mg, p < 0.0001) and (3247 ± 353.2 vs. 690.4 ± 201.6 mm3, p < 0.001) (Fig. 7).