NPPA and infection: By univariate analysis, including markers of inflammation/infection (CRP, p = 0.111; lactate, p = 0.198), hepatic (bilirubin, p = 0.161) and renal (creatinine, p = 0.427) function at admission were not significantly associated with mortality, while MR-proANP showed highest prognostic value (p = 0.013) for ICU mortality.