Based on the current in vitro and animal research evidence, phenolic acid, C-21 steroidal glycosides, and polyphenols in MTE may play a critical role in its anticancer mechanism, which could suppress angiogenesis in cancer tissues by blocking the activation of vascular endothelial growth factor receptors and phosphorylated protein kinases [12, 37, 38]. Here, WEE1 is linked to cancer.