Furthermore, terpenes are the second most common abundant components of Decatropis bicolor leaf extracts, which triggered apoptosis in MDA-MB-231 breast cancer cell line, through a Bax/Bcl2 dependent mechanism, translated by a dose-dependent upregulation of Bax, and downregulation of Bcl2 [55], similar to what was observed in our study. This evidence concerns the gene BCL2 and breast cancer.