SCN1A and Dravet syndrome: Other GABA neuron-selective gene regulatory elements have been described, for example, the Dlx family of enhancers that participate in the development of GABAergic neurons in the telencephalon at early developmental stages.27,28 However, the Dlx elements might not be optimal for treating DS because they are reported to be operative only in forebrain regions,27,28 while NaV1.1 channels are found throughout the CNS, including in more caudal regions such as the cerebellum and brain stem.13