Autophagy is closely connected to a variety of human disease and physiology, including HCC.29 According to previous study, combination treatment of MET and sorafenib could suppress proliferation and induce autophagy of HCC cells through targeting the mTOR.12 In this research, MET was proved to promote autophagy in HepG2 and Bel‐7402 cells and in tumors. Here, MTOR is linked to hepatocellular carcinoma.