And they found that implantation of Ad5/3-B4GALNT2 vectors into the abdominal cavity of mice after inoculation of KATO III cells by surgery could reduce the incidence of PM significantly, which indicated that delivery of a single gene encoding B4GALNT2 modified carbohydrate chains of tumor cells in vivo and reduced cancer metastasis and dissemination. The gene discussed is B4GALNT2; the disease is cancer.