RAMRIS of synovitis was significantly correlated with 28TJC, 28SJC, ESR, CRP, DAS28-CRP, SDAI, and CDAI (r = 0.262~0.400, all p < 0.05, Additional file 1: Table S1); RAMRIS of tenosynovitis was slightly but significantly correlated with 28TJC, CRP, DAS28-CRP, and SDAI (r = 0.269~0.282, all p < 0.05); and osteitis score was only slightly correlated with CRP (r = 0.242, p < 0.05). The gene discussed is CRP; the disease is synovitis.