While the mechanism by which CCNG2 inhibits LPR6 and DVL2 in EOC is not known, a recent report in gastric cancer indicated that CCNG2 downregulated DVL2 through the interaction with Dapper1 (DACT1) [54], a Wnt signalling antagonist that has been shown to promote DVL2 degradation [55]. Here, DACT1 is linked to gastric cancer.