Li and colleagues studied the morphological changes, histone methylation alterations and cell growth‐related signalling pathway in the inferior facet joint cartilage in 10 control subjects and 11 patients with idiopathic scoliosis.53 Patients with idiopathic scoliosis showed increased number of proliferative chondrocytes as well as upregulation of BCL2 and COL2A1 in the facet joint cartilage, which was significantly narrowed. Here, BCL2 is linked to idiopathic scoliosis.