For instance, ZEB1‐AS1 promotes the tumorigenesis of glioma by regulating the miR‐200c/141‐ZEB1 axis.34 ZEB1‐AS1 also facilitates melanoma progression by regulating miR‐1224‐5p.28 Here, we showed that ZEB1‐AS1 directly binds to miR‐455‐3p in COAD cells. This evidence concerns the gene ZEB1 and melanoma.