Current strategies to treat DKD recommend multifactorial management including blood pressure control with renin-angiotensin system inhibitors and hypoglycemic agents like insulin, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium glucose cotransporter type 2 (SGLT2) inhibitors, glucagon-like peptide 1 (GLP1), lipid control, and dietary restrictions [15]. This evidence concerns the gene DPP4 and diabetic kidney disease.