These abnormalities are primarily due to CKD-induced dysregulation of several important proteins such as lecithin-cholesterol acyltransferase (LCAT) [17, 18], scavenger receptor class B type 1 (SR-B1) [19–21] and ATP binding cassette A1 (ABCA1) [22]. The gene discussed is SCARB1; the disease is chronic kidney disease.