Additionally, we confirmed these results by qRT-PCR experiments (Figures 2(c) and 2(d)) showing significant overexpression for XAF1, the TRAIL encoding gene TNFSF10 and STAT1 along with a downregulation of SOCS3 in miR-221 overexpressing PCa cells. The gene discussed is XAF1; the disease is posterior cortical atrophy.