Seven of the 12 genes, namely, FABP3, GALNT5, GPR84, ITGB6, MYEOV, PLEKHS1, and STRA6, can be perceived as candidate genes for the prognostic prediction of HCC, which have not been previously reported for their prognostic value in HCC patients. Here, PLEKHS1 is linked to hepatocellular carcinoma.