ITGB6 and Hepatic fibrosis: Among the seven potential biomarkers FABP3, GALNT5, GPR84, ITGB6, MYEOV, PLEKHS1, and STRA6, we are particularly interested in GPR84 and STRA6 because they link to liver fibrosis that is a major risk factor in HCC and an independent risk factor of recurrence after hepatectomy [43, 44].