Surprisingly, between more than 30 types of cancer, only pancreatic adenocarcinoma (PAAD or PDAC) shows a significant increase of p38α, p38β, and p38γ compared with healthy control pancreas (red labeled, Figure 1A, Figures S1A,B), suggesting that p38 MAPKs may be involved in PDAC development. This evidence concerns the gene MAPK14 and cancer.