ACTBL2 and colorectal cancer: Ghazanfar et al. (36) performed two-dimensional gel electrophoresis coupled with mass spectrometry for the expression profiling of proteins extracted from freshly frozen human colorectal cancer tissue specimens (12 patients) and neighboring non-tumor tissue, and they demonstrated the upregulation of some proteins, such as actin beta-like 2 (ACTBL2), in colorectal cancer.