Quesada-Calvo et al. (23) analyzed 76 formalin-fixed paraffin-embedded colorectal tissues from early CRC stages (pT1N0M0 and pT2N0M0), as well as normal or inflamed mucosa, by label-free proteomics, and different expression levels of olfactomedin-4 (OLFM4), kininogen-1 (KNG1), and transport protein Sec24C (Sec24C) were observed in the early CRC stages compared to normal and premalignant tissues. The gene discussed is OLFM4; the disease is colorectal carcinoma.