LGR5 and neoplasm: The tumor cells of 88 (87.1%, valid n = 101) primary GCs, 54 (77.1%, valid n = 70) lymph node metastases, 10 (100%, valid n = 10) distant metastases, and 21 (87.5%, valid n = 24) pretherapeutic biopsies showed a cytoplasmic expression of LGR5.