Moreover, to evaluate Toll-like receptor- (TLR-) mediated autophagy induction in intestinal epithelial cells (IEcs) and CRC cells as well as its relationship with proinflammatory productions of CXCL8, IEC-6, and HCT-15, cells were cultured with or without various TLR ligands, followed by evaluation of the expressions of CXCL8 by ELISA and real-time PCR. This evidence concerns the gene CXCL8 and colorectal carcinoma.