CXCL8 and colorectal carcinoma: To study the role of the migration of CXCL8 into the tumor tissue of dendritic cells (DC), Alfaro and colleagues [38] developed mice whose peritoneums were injected with CRC cell lines, HT29 cells, CaCo2 cells, or SW480 cells, to induce subcutaneous tumors, and then, fluorescence-labeled DC was injected into the subcutaneous tissue 5 mm away from the tumor.