Additionally, Ning et al. [15] inhibited the overexpression of CXCL8 in CRC cells by using small interfering RNA and found that the phenomenon of cancer cells resistant to oxaliplatin was significantly reduced, suggesting that the overexpression of CXCL8 in the cancer cells caused obvious resistance to oxaliplatin. This evidence concerns the gene CXCL8 and colorectal carcinoma.