CXCL8-mediated tumor progression, occurring primarily through CXCR1 and CXCR2, has been identified as a function of the modulation of angiogenesis, immune cell infiltration, cell motility, cell survival, and growth in the microenvironment as well as the regulation of local antitumor immune responses [7–9]. This evidence concerns the gene CXCR1 and neoplasm.