When compared with those without, T2DM patients with DPN had significantly more men, older age, longer diabetic duration, larger proportions of hypertension, CHD, stroke, DFU, PAD, DN, and DR, higher levels of blood pressure, glycemic control, reflected by FBG and HbA1c, ApoB/ApoA, neutrophil count, WBC, NLR, coagulation index, urinary ACR, Crea and VPT values, and lower levels of BMI, DBP, TC, TG, ApoA, TBIL, DBIL, IBIL, eGFR, liver enzymes, lymphocyte count, and ABI (P < 0.01 or P < 0.05). This evidence concerns the gene APOB and Hypertension.