A negative correlation of serum TBIL with diabetic duration, PP, TG, ApoB/ApoA, neutrophil and WBC counts, NLR, fibrinogen, urinary ACR, VPT values, and the prevalence of hypertension, DFU, DPN, DN and DR was also observed (P < 0.01 or P < 0.05). The gene discussed is APOB; the disease is hypertensive disorder.