In all T2DM patients, serum TBIL levels were positively associated with DBP, TC, HDL-C, ApoA, LDL-C, DBIL, IBIL, liver enzymes, and eGFR, and negatively with age, sex, diabetic duration, PP, TG, ApoB/ApoA, neutrophil and WBC counts, fibrinogen, urinary ACR, Crea, VPT values, and the prevalence of hypertension, DFU, PAD, DPN, DN and DR (P < 0.01 or P < 0.05; Table 2). This evidence concerns the gene APOB and hypertensive disorder.