OTOF and auditory neuropathy: As the mutation spectrum of the OTOF gene shows great discrepancies between different countries and ethnic populations, including high frequencies of the mutation p.E1700Q in Chinese from Taiwan [5], p.R1939Q in Japanese [6, 17], p.Val1778Phe in Ashkenazi Jewish [18], Q829X in Spanish [19], c.2905-2923delinsCTCCGAG-CGCA in Argentinean [9], and p.R1792H in Saudi Arabian [20], understanding of the molecular mechanism of ANSD needs to be improved.