KEGG: TGF-beta signaling pathway Reactome: Signaling by BMP (Bone morphogenetic proteins) GAD: Albumins, body height, bone mineral density, cleft lip, gamma-glutamylcyclotransferase, height, neural tube defects, nonsyndromic cleft lip with or without cleft palate, obesity|POF–premature ovarian failure|polycystic ovarian syndrome|polycystic ovary syndrome|primary ovarian insufficiency|puberty, delayed|puberty, precocious|thrombophilia|tobacco use disorder, osteoporosis GAD class: developmental, metabolic. The gene discussed is GGCT; the disease is obesity due to melanocortin 4 receptor deficiency.