As the growth of UEV1A-overexpressed MDA-MB-231-TR (Fig. 3f) or MCF7 (Fig. 3g) cells under serum-deprived conditions was still significantly different from that of vector control cells after treatment with Bay11-7082, indicating that Uev1A promoted breast cancer cell survival under serum starvation stress is independent of the NF-κB pathway. The gene discussed is UBE2V1; the disease is breast carcinoma.