E2F1 and cervical cancer: Our data suggested that E2F1 and Myc’s mRNAs were significantly enriched in FTO regulated transcripts (Fig. 5a), all these results confirmed that the cervical cancer drivers such as E2F1 and Myc were dynamically modified by m6A methylation, while as an “eraser”, FTO could directly regulate these mRNAs demethylation as m6A modification in E2F1 and Myc transcripts were significantly increased when FTO was inhibited (Fig. 5b).