PDCD1 and non-small cell lung carcinoma: The clinical trials CheckMate 017, CheckMate 057, and Keynote 010 demonstrated that the monoclonal antibodies (mAbs) against programmed cell death-1 (PD-1) nivolumab [9] and pembrolizumab [10] significantly improved the overall survival (OS) over docetaxel in NSCLC patients after the failure of prior platinum-based chemotherapy.