TNF and type 2 diabetes mellitus: Nevertheless, after training, there was an increase in neutrophil TNF-α (30% in patients with T2DM) (Figure 2(a)) and IL-8 (20% in controls) (Figure 2(b)) production, and neutrophil IL-6 production was lower (60% in controls and 50% in patients with T2DM) in both groups following LPS stimulation (Figure 2(c)).