Of interest, sons of women with PCOS examined over pubertal development exhibit higher cholesterol and LDL levels, but do not present with any differences in circulating concentrations of LH, FSH sex hormone-binding globulin, testosterone, androstenedione (A4), 17α-hydroxyprogesterone (17-OHP) or AMH49. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.