IGFBP7 and acute myeloid leukemia: In line with these findings, Dunne et al. [28] have demonstrated the impact of RUNX1-ETO silencing on the expression of genes associated with proliferation and differentiation, such as Insulin-like growth factor-binding protein 7 (IGFBP7) and Cathepsin G (CTSG), in Kasumi-1 and patient derived AML blasts with t(8;21) by oligonucleotide array and qRT-PCR.