Given these studies and our work, it is conceivable that dysregulated deamidated 4E-BP2 degradation, as a result of altered mTORC1 signaling during development, could be linked to a prodromal period of neurodevelopmental disorders such as ASDs (via aberrant translational control of neuronal mRNAs). Here, EIF4EBP2 is linked to neurodevelopmental disorder.