In cancer cells, DEPDC1B affects WNT/β‐catenin signalling33 a pathway also involved in satellite cell regulation.47, 48 Therefore, we performed a double DEPDC1B/β‐catenin siRNA‐mediated knockdown rescue experiment in murine satellite cells, to test whether the reduced proliferation/precocious differentiation observed by knocking down DEPDC1B alone could be attributed to activation of β‐catenin. This evidence concerns the gene DEPDC1B and cancer.