ACE and heart failure: Heart failure prevalence is as high as 13% in patients over the age of 80.30 Treatment guidelines for heart failure with reduced ejection fraction (HFrEF, LVEF <40%) recommend chronic use of RAAS inhibitors (ie, ACE‐i, ARB, Angiotensin Receptor‐Neprilysin Inhibitor [ARNI], aldosterone antagonists) and beta‐blockers to reduce morbidity and mortality.30, 38 However, treatments for heart failure with preserved ejection fraction (HFpEF, LVEF >50%) rely largely on fluid management with diuretics and optimization of associated comorbidities.