In this study, we found that dynamin-dependent Stx2 endocytosis had no relevance on Stx2 uptake (Figure 2) or cytotoxic effects when O157:H7Δstx2 was absent but did significantly contribute to Stx2 cytotoxicity upon O157:H7Δstx2 infection (Figure 3). The gene discussed is STX2; the disease is infection.