CTSB and neoplasm: Likewise, 75% (30/40) of GBC cases also exhibited higher CTSB expression (H-score >4) in tumor endothelial cells as compared to only 11% (7/60) of controls, implying significant overexpression of CTSB protein (p < 0.0001, Figures 4H,I, Table 3) in this malignancy.