Further, Chiung-Yuan Ko et al. (147) showed that YY1 upon interacting with suppressor of Zeste 12 (SUZ12) recruits polycomb repressive complex to the promoter of the tumor suppressor gene CEBPD (148) to repress its expression in HCC and thereby promotes HCC growth. The gene discussed is CEBPD; the disease is hepatocellular carcinoma.