For example, the MALAT-1 gene is upregulated in HCC and also correlates with prognostics and recurrence (Guerrieri, 2015; Lai et al., 2012); the overexpression of the HULC gene may reduce the mir-372 gene, while at the same time may promote reprogramming during tumorigenesis (Du et al., 2012); and DANCR induces stemness features and could serve as a potential prognostic marker and therapeutic target for HCC (Yuan et al., 2016). The gene discussed is MALAT1; the disease is hepatocellular carcinoma.