The GO and KEGG enrichment analysis concerning the target genes of lncRNAs indicated that the top regulated pathways of lncRNAs were Huntington’s disease, RNA polymerase and Pyrimidine metabolism, and the top regulated functions of lncRNAs were SRP-dependent co-translational protein targeting to membrane, translational initiation, viral transcription, nuclear-transcribed mRNA catabolic process, and nonsense-mediated decay. The gene discussed is UCN2; the disease is juvenile Huntington disease.