One study applied a panel of methylation markers (EYA4, GRIA4, ITGA4, MAP3K14-AS1, and MSC) (Barault et al., 2018) in 25 patients, and the other measured methylated MGMT in 29 patients with MGMT promoter hypermethylation of tumor tissue (Amatu et al., 2016). This evidence concerns the gene MGMT and neoplasm.