In accordance with the increased FR-β expression, we also found increased CD68 expression in lung sections from both IPF and CTD-ILD patients with median increases of 1.69-fold (Q1, Q3 = 1.37, 2.29; p < 0.0001) and 1.89-fold (Q1, Q3 = 1.09, 2.8; p < 0.01), respectively (Figure 1D, Supplementary Figure 2B). This evidence concerns the gene FOLR2 and interstitial lung disease.