Furthermore, while the upregulation of CD68 and FR-β in IPF and CTD-ILD patients was independent of the histological subtype (Supplementary Figure 3), the expression of FR-β significantly increased with the severity of lung remodeling (Figure 1F) and positively correlated with the Ashcroft score as measure of lung remodeling (r = 0.84, p < 0.0001; Figure 1G). Here, FOLR2 is linked to idiopathic pulmonary fibrosis.