Likewise, MAIT cells from MS patients showed increased MFI for different adhesion molecules and integrins, especially those involved in the first step of lymphocyte extravasation into CNS, including VLA-4 (CD49d), LFA-1 (CD11a), PSGL-1 (CD162), and LFA-3 (CD58), compared to HCs (p < 0.05 to p < 0.0001; Figure 2B). Here, ITGAL is linked to myeloid sarcoma.