CFTR and cystic fibrosis: Cystic fibrosis (CF) is the most common life-limiting genetic disorder within the Caucasian population (Cystic Fibrosis Foundation, 2019), with 1 in 40 people estimated to carry the common ΔF508 mutation in the CF transmembrane conductance regulator (CFTR) gene (Bobadilla et al., 2002; Cystic Fibrosis Mutation Database, 2019).