Feeding zebrafish with similar combined diet for 7, 14, or 21 days also increased the expression antimicrobial peptide genes, defensin beta-like 1 (defbl1), defbl2, defbl3, and hepcidin after infection, suggesting the potential of Epi-1 to be a promising therapeutic agent for V. vulnificus (204) infection (Jheng et al., 2015). This evidence concerns the gene HAMP and infection.