Regarding its role in AD, resistin is reported to increase the expression of monocyte chemoattractant protein 1 (MCP-1), vascular cell adhesion molecule 1 (VCAM-1), and intercellular adhesion molecule 1 (ICAM-1) in endothelial cells, which contributes to inflammation in AD (116). The gene discussed is RETN; the disease is Alzheimer disease.