FMOD and breast carcinoma: Our present study clearly shows that Aspirin inhibits breast cancer cell migration and invasion via attenuating the Wnt/β-catenin signaling pathway to suppress transcription of FMOD, a newly identified target gene of the pathway, which establishes Wnt/β-catenin signaling pathway-mediated FMOD expression as a mechanism underlying the anti-metastasis effects of Aspirin in breast cancer.