In contrast, a recent more comprehensive study on FMOD in glioblastoma (GBM) indicated that FMOD is required for glioma cell migration, and that FMOD induces glioma cell migration induced by FMOD occurred via the activation of the FAK-Src-Rho-ROCK signaling pathway (Mondal et al., 2017). Here, PTK2 is linked to central nervous system cancer.