FMOD and cancer: Our present findings reveal important roles and inter-relationships of the ECM component FMOD, the Wnt/β-catenin signaling pathway and the NSAID drug Aspirin in BCCMI, which is summarized by a schematic model depicting Aspirin and the Wnt/β-catenin signaling pathway regulating fibromodulin (FMOD) expression and cancer metastasis (Figure 9F).