In a cohort of 32 small cell lung cancer (SCLC) BrM specimens, a dense accumulation of CD3+, CD8+, and CD45RO+ T cells in the perivascular area was observed, while FOXP3+ TILs were more abundant within the tumor area and less within the perivascular area (Berghoff et al., 2016b). This evidence concerns the gene CD8A and neoplasm.