Huntington’s disease is an inherited neurodegenerative disease that severely impacts motor function and often impairs cognition (La Spada et al., 2011; Caron et al., 2018), which is caused by an autosomal dominant mutation in the huntingtin gene that gives rise to a CAG trinucleotide repeat expansion (Schulte and Littleton, 2011). Here, HTT is linked to Huntington disease.