ZBTB7A and cancer: An additional interesting mechanism related to the LRF/ZBTB7A’s oncosuppressive functions involves the transcriptional repression of key oncogenic glycolytic genes like glucose transporters 1 and 3 (GLUT1, GLUT3), phosphofructokinase (PFKP), and pyruvate kinase muscle isozyme (PKM), thereby inhibiting cancer metabolism [33, 34].