Furthermore, HP1γ-induced downregulation of the LRF/ZBTB7A favors the expression of several tumor-promoting factors, such as AXL receptor tyrosine kinase (AXL), plasmacytoma variant translocation 1 (PVT1), and ETS Like-1 protein (ELK1) [87]. This evidence concerns the gene ZBTB7A and neoplasm.